HIPOVITAMINOSE D PDF

PDF | On Oct 1, , Roberta Vanacor and others published Pacientes com hipovitaminose D podem não ter hiperparatireoidismo secundário. Objetivos: Analisar os níveis séricos de vitamina D em pacientes obesos em Hipovitaminose D em adultos: entendendo melhor a apresentação de uma velha . Veja grátis o arquivo Hipovitaminose D enviado para a disciplina de Bioquímica Categoria: Aulas – 12 –

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Hipovitaminose D em adultos: Vitamin D deficiency in adults: Vitamin D is synthesized in skin through a reaction mediated by sunlight, and it is metabolized to hydroxyvitamin D, in liver, and in 1,dihydroxyvitamin D, in kidney.

This last reaction has a tight feedback mechanism. Its major functions are in calcium metabolism and bone mass maintenance. Hypovitaminosis D, as a disease in adult people, hipovitaminosse itself with hypocalcemia and secondary hyperparathyroidism with subsequent loss of trabecular bone, thinning of cortical bone, and, eventually, a higher risk of fractures.

Measurement of serum total hydroxyvitamin D concentration is the gold standard to diagnose vitamin D deficiency. Risk factors for vitamin D deficiency, like poor sunlight exposition, aging skin and factors that interfere with normal vitamin D metabolism, are well established.

Oral vitamin D supplementation, an easy and inexpensive treatment, is needed to treat this illness.

Fisiologia da Vitamina D. Vitamina D e seus Receptores. Assim, a parte mineralizada do osso cortical torna-se mais fina. Nesta fase, a 1,25 OH 2 D pode estar normal ou elevada Fatores de Risco para Hipovitaminose D.

Todavia, Guinot e col. Talvez idosos necessitem de doses ainda maiores, como a 1. Um dos estudos mais importantes foi o realizado por Marie Chapuy e col. Estas doses poderiam ser A vitamina D pode ser adicionada aos alimentos, principalmente ao leite. Vitamin D and Rickets. Structure-function relationships in the vitamin D endocrine system.

PREVALENCE OF OSTEOPOROSIS AND HYPOVITAMINOSIS D AT SIRIRAJ METABOLIC BONE DISEASE CLINIC.

Endocr Rev ; On becoming a molecular endocrinologist. Nishii Y, Okano T. History of the development of new vitamin D analogs: Photobiology, metabolism, and clinical applications.

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Prosser DE, Jones G. Enzymes involved in the activation and inactivation of vitamin D.

Trends Biochem Sci ; Overview of regulatory cytochrome P enzymes of the vitamin D pathway. Basic and clinical concepts related to vitamin D metabolism and action second of two parts. N Engl J Med hhipovitaminose The role of 1,dihydroxyvitamin D in the mechanism of acquired vitamin D deficiency. Clin Endocrinol Oxf ; Different shapes of the steroid hormone 1alpha,25 OH 2 -vitamin D 3 act as agonists for two different receptors in the vitamin D endocrine system to mediate genomic and rapid responses.

Vitamin D receptor and nuclear receptor coactivators: Crucial interactions in vitamin D-mediated transcription. Three-dimensional structure-function relationship of vitamin D and vitamin D receptor model. Why do we need a three-dimensional architecture of the ligand-binding domain of the nuclear 1alpha,dihydroxyvitamin Hipovitaminoss 3 receptor?

Central role of VDR conformations for understanding selective actions of vitamin D 3 analogues. Extra-endocrine functions of vitamin D. Newly identified actions of the vitamin D endocrine system.

Hipovitaminose D

Vitamin D and muscle function. Osteoporos Int ; Plasma creatinine and creatinine clearance in nutritional osteomalacia. Regulatory effects of 1alpha,dihydroxyvitamin D3 on the cytokine production of human peripheral blood lymphocytes.

J Clin Endocrinol Metab ; Metabolism of 1alpha,dihydroxyvitamin D 3 in human promyelocytic leukemia HL cells: In vitro biological activities of the natural metabolites of 1alpha,dihydroxyvitamin D 3 produced in HL cells.

Vitamin D and breast cancer: Insights from animal models. Am J Clin Nutr ;80 Suppl. Vitamin D and skin cancer. J Nutr ; Suppl. Vitamin D and colon carcinogenesis.

The role of Vitamin D3 metabolism in prostate hipovitamiose. J Steroid Biochem Mol Biol ;92 4: Peehl DM, Feldman D. Interaction of nuclear receptor ligands with the Vitamin D signaling pathway in prostate cancer. Beer TM, Myrthue Hipovitaminpse. Calcitriol in cancer treatment: Mol Cancer Hipovitaminlse ;3 3: Plasma calcidiol, season, and serum parathyroid hormone concentrations in healthy elderly men and women. Am J Clin Nutr ; Effects of age, sex, season and diet on serum ionized calcium, parathyroid hormone and vitamin D in a random v.

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J Inten Med ; Subclinical vitamin D deficiency in postmenopausal women with low vertebral bone mass. Seasonal variation of biochemical indexes of bone turnover: Results of a population-based study. Secondary hyperparathyroidism in elderly people: Combined effect of renal insufficiency and vitamin D deficiency. Serum vitamin D metabolites and calcium absorption in normal young and elderly free-living women and in women living in nursing homes.

Vitamin D deficiency and secondary hyperparathyroidism in the elderly: Single-dose cholecalciferol suppresses the winter increase in parathyroid hormone concentrations in healthy older men and women: An evaluation of the relative contributions hipoviyaminose exposure to sunlight and of diet to the circulating concentrations of hydroxyvitamin D in an elderly nursing home population in Boston.

Serum vitamin D2 and vitamin D3 metabolite concentrations and absorption of vitamin D2 in elderly subjects. Age-related endocrine deficiencies and fractures of the proximal femur. II implications of vitamin D deficiency in the elderly. J Endocrinol ; Plasma hydroxy vitamin D concentrations in patients with fractures of the femoral neck. The microanatomy of trabecular bone loss in normal aging men and women.

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Clin Orthop Relat Res Age related histomorphometric changes in bone in normal British men and women. J Clin Pathol ; Muscle weakness in intensive care patients: Initial manifestation of vitamin D deficiency. Intensive Care Med ; Evidence of gene-environment interaction in development of tuberculosis.

High-performance liquid chromatographic assay for hydroxyvitamin D3 in serum. Clin Chem ; Osadca M, Araujo M.