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Hipovitaminose D em adultos: Vitamin D deficiency in adults: Vitamin D is synthesized in skin through a reaction mediated by sunlight, and it is metabolized to hydroxyvitamin D, in liver, and in 1,dihydroxyvitamin D, in kidney.
This last reaction has a tight feedback mechanism. Its major functions are in calcium metabolism and bone mass maintenance. Hypovitaminosis D, as a disease in adult people, hipovitaminosse itself with hypocalcemia and secondary hyperparathyroidism with subsequent loss of trabecular bone, thinning of cortical bone, and, eventually, a higher risk of fractures.
Measurement of serum total hydroxyvitamin D concentration is the gold standard to diagnose vitamin D deficiency. Risk factors for vitamin D deficiency, like poor sunlight exposition, aging skin and factors that interfere with normal vitamin D metabolism, are well established.
Oral vitamin D supplementation, an easy and inexpensive treatment, is needed to treat this illness.
Fisiologia da Vitamina D. Vitamina D e seus Receptores. Assim, a parte mineralizada do osso cortical torna-se mais fina. Nesta fase, a 1,25 OH 2 D pode estar normal ou elevada Fatores de Risco para Hipovitaminose D.
Todavia, Guinot e col. Talvez idosos necessitem de doses ainda maiores, como a 1. Um dos estudos mais importantes foi o realizado por Marie Chapuy e col. Estas doses poderiam ser A vitamina D pode ser adicionada aos alimentos, principalmente ao leite. Vitamin D and Rickets. Structure-function relationships in the vitamin D endocrine system.
PREVALENCE OF OSTEOPOROSIS AND HYPOVITAMINOSIS D AT SIRIRAJ METABOLIC BONE DISEASE CLINIC.
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